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P1-2-16 Permanent Neonatal Diabetes Mellitus Due To A G32s Heterozygous Mutation Within The Insulin Gene
However, it is a very important complication of hypothyroidism occurring in childhood. NR0B1 mutations doubtless underlie testosterone overproduction by way of both GnRH-dependent and -independent mechanisms. Their capability to inhibit (typically in maternal autoimmune atrophic thyroiditis) or activate (in maternal Graves-Basedow thyrotoxicosis) TSH receptor. We focused on nucleotide alterations that have an effect on protein sequences or splice websites. Nucleotide modifications whose frequency within the basic inhabitants is more than 1.0% had been excluded as widespread polymorphisms. Functional penalties of missence variants had been predicted by two in silico assays.
P1-1-6 The Cutoff Values Of Oblique Indices For Measuring Insulin Resistance In Korean Youngsters And Adolescents
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